SCHEMBL21295845

SCHEMBL21295845

[c]1ccc2c(c1)sc1c(-c3ccncc3)cccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
TDO2 P48775 1/20 0.37
PDE10A Q9Y233 3/20 0.36
PIK3CD O00329 1/20 0.35
CYP17A1 P05093 1/20 0.33
CYP1A2 P05177 1/20 0.33
IMPDH2 P12268 2/20 0.33
LIMK1 P53667 1/20 0.33
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 2/20 0.33
BACE1 P56817 1/20 0.32
BACE2 Q9Y5Z0 1/20 0.32
PARP14 Q460N5 1/20 0.32
GSK3B P49841 3/20 0.32
CDK2 P24941 2/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21296094 0.89 ALOX5 (0.40) ALOX5TDO2PDE10APIK3CDCYP17A1
SCHEMBL21295599 0.87 ALOX5 (0.46) ALOX5PIK3CDCYP17A1CYP1A2LIMK1
SCHEMBL21296065 0.85 ALOX5 (0.40) ALOX5PDE10ACYP1A2LIMK1GSK3B
SCHEMBL20441890 0.82 ALOX5 (0.56) ALOX5TDO2PDE10APIK3CDCYP17A1
SCHEMBL21295709 0.80 PIK3CD (0.35) PIK3CDIMPDH2LIMK1KDM4ENPC1
SCHEMBL15987505 0.75 ALOX5 (0.56) ALOX5PIK3CDLIMK1PARP14ALDH1A1
SCHEMBL29293020 0.75 LIMK1 (0.53) ALOX5TDO2PDE10APIK3CDCYP17A1
SCHEMBL21295750 0.75 ALOX5 (0.46) ALOX5PIK3CDCYP17A1CYP1A2LIMK1
SCHEMBL28570273 0.75 GPR3 (0.39) ALOX5PDE10ACYP17A1CYP1A2IMPDH2
SCHEMBL21295906 0.74 TDO2 (0.39) ALOX5TDO2PDE10APIK3CDCYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed