SCHEMBL21295949

SCHEMBL21295949

C=C(C)C(=O)OCC(CCF)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28557383 0.87 TSHR (0.46) TSHRTHRBALDH1A1
SCHEMBL8163873 0.84 TSHR (0.46) TSHRTHRB
SCHEMBL6131172 0.79 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL28688493 0.79 TSHR (0.51) TSHRTHRBALDH1A1
SCHEMBL1415511 0.79 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL9873757 0.77 THRB (0.41) TSHRTHRB
SCHEMBL12200557 0.76 TSHR (0.45) TSHRTHRB
SCHEMBL3098779 0.75 TSHR (0.44) TSHRTHRBALDH1A1
SCHEMBL711903 0.72 TSHR (0.46) TSHRTHRBALDH1A1
SCHEMBL15666080 0.71 TSHR (0.53) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019163804-A1 CURABLE COMPOSITION 株式会社カネカ 2019-08-29 WO disclosed