SCHEMBL21296087

SCHEMBL21296087

CO[Si](OC)(OC)C(CSC#N)Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.36
TAAR1 Q96RJ0 4/20 0.33
SLC6A2 P23975 2/20 0.33
ANPEP P15144 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
MAOA P21397 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP2A6 P11509 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
EGFR P00533 1/20 0.32
LAP3 P28838 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SLC18A2 Q05940 1/20 0.32
CYP2D6 P10635 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233079 0.81 MAOB (0.42) MAOBTAAR1SLC6A2ANPEPSIGMAR1
SCHEMBL6332012 0.75 TRPA1 (0.43) TAAR1SLC6A2SIGMAR1MAOASLC6A4
SCHEMBL2111677 0.74 ANPEP (0.46) TAAR1SLC6A2ANPEPSIGMAR1MAOA
SCHEMBL485619 0.74 TAAR1 (0.39) TAAR1SLC6A2SIGMAR1MAOASLC6A4
SCHEMBL27769938 0.74 TAAR1 (0.39) TAAR1SLC6A2SIGMAR1MAOASLC6A4
SCHEMBL614445 0.71 ALDH1A1 (0.49) TAAR1SLC6A2ANPEPSIGMAR1MAOA
SCHEMBL1730609 0.69 TAAR1 (0.50) TAAR1SLC6A2ANPEPSIGMAR1MAOA
SCHEMBL16597964 0.68 TAAR1 (0.38) TAAR1SLC6A2SIGMAR1MAOASLC6A4
SCHEMBL28531050 0.68 SLC6A2 (0.38) TAAR1SLC6A2SIGMAR1MAOASLC6A4
SCHEMBL1579546 0.68 TAAR1 (0.34) MAOBTAAR1SLC6A2SIGMAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075101-A1 SURFACE TREATMENT Interphase Materials, Inc (US) 2025-03-06 US disclosed
US-12146071-B2 Surface treatment INTERPHASE MATERIALS INC. (US) 2024-11-19 US disclosed
EP-4106913-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR SAMPLE PROCESSING 10X Genomics, Inc. (US) 2022-12-28 EP disclosed
US-20220016624-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR SAMPLE PROCESSING 10X GENOMICS, INC. 2022-01-20 US disclosed
EP-3697860-A2 SURFACE TREATMENT Interphase Materials Inc. (US) 2020-08-26 EP disclosed
US-20200231842-A1 Surface Treatment INTERPHASE MAT INC (US) 2020-07-23 US disclosed
WO-2019164546-A2 SURFACE TREATMENT INTERPHASE MATERIALS INC. (US) 2019-08-29 WO disclosed