Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 11/20 | 0.67 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | AHR | P35869 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.55 |
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898375 | 0.81 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL29551999 | 0.81 | HSD17B1 (0.88) | HSD17B1HSD17B2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL69369 | 0.81 | HSD17B1 (0.88) | HSD17B1HSD17B2CYP3A4CYP2C9HSD17B10 | |
| Hydrochloric Acid SCHEMBL2461057 | 0.80 | CA12 (0.59) | HSD17B1HSD17B2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL1028579 | 0.80 | HSD17B1 (0.77) | HSD17B1HSD17B2CYP3A4CYP2C9ESR2 | |
| SCHEMBL6335821 | 0.79 | AHR (0.70) | HSD17B1HSD17B2AHRHSD17B10ESR2 | |
| SCHEMBL8050006 | 0.78 | HSD17B1 (0.94) | HSD17B1HSD17B2CYP3A4CYP2C9HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28150307 | 0.78 | HSD17B1 (0.83) | HSD17B1HSD17B2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL29769221 | 0.78 | AHR (1.00) | CYP3A4AHRHSD17B10ESR2CYP1B1 | |
| SCHEMBL137915 | 0.78 | AHR (1.00) | CYP3A4AHRHSD17B10ESR2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | OXALURX, INC. (US) | 2022-07-19 | — | — | US | disclosed |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2019165159-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
| CN-109761757-A | A kind of synthetic method of chlorophenesic acid | 山东润博生物科技有限公司 | 2019-05-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, LOX | HSD17B1 553/4885HSD17B2 821/4885CYP3A4 2004/4885 |
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | XDH, PNPO, LOX | HSD17B1 553/4885HSD17B2 821/4885CYP3A4 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.