SCHEMBL21297

SCHEMBL21297

Nc1ccc(-c2ccc(N)c(N)c2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.78
MEN1 O00255 3/20 0.78
KMT2A Q03164 3/20 0.78
CYP3A4 P08684 8/20 0.61
ALDH1A1 P00352 6/20 0.61
TP53 P04637 2/20 0.61
KCNH2 Q12809 2/20 0.52
HSD17B10 Q99714 3/20 0.50
TAAR1 Q96RJ0 2/20 0.50
CYP17A1 P05093 2/20 0.50
CYP19A1 P11511 2/20 0.50
CYP11B1 P15538 2/20 0.50
CYP11B2 P19099 2/20 0.50
PKM P14618 1/20 0.46
HTR6 P50406 1/20 0.46
ALOX15 P16050 4/20 0.46
TSHR P16473 3/20 0.46
MAPT P10636 2/20 0.44
MAPK1 P28482 1/20 0.44
KIF11 P52732 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL7595155 0.97 TDP1 (0.74) TDP1MEN1KMT2ACYP3A4ALDH1A1
Hydrochloric Acid SCHEMBL6207952 0.97 TDP1 (0.74) TDP1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL12772920 0.91 TDP1 (0.93) TDP1MEN1KMT2ACYP3A4ALDH1A1
Hydrochloric Acid SCHEMBL1646515 0.88 TDP1 (0.88) TDP1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL23855 0.88 TDP1 (1.00) TDP1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL29349835 0.88 TDP1 (1.00) TDP1MEN1KMT2ACYP3A4ALDH1A1
SCHEMBL8745318 0.85 TDP1 (0.93) TDP1MEN1KMT2ACYP3A4ALDH1A1
Hydrochloric Acid SCHEMBL874057 0.85 TDP1 (0.93) TDP1MEN1KMT2ACYP3A4ALDH1A1
Hydrochloric Acid SCHEMBL504482 0.85 TDP1 (0.93) TDP1MEN1KMT2ACYP3A4ALDH1A1
Water SCHEMBL10589317 0.85 TDP1 (0.93) TDP1MEN1KMT2ACYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115975138-A Microporous covalent organic framework material based on quinoxaline and imine bond connection and preparation method thereof 北京理工大学 2023-04-18 CN claimed
CN-110041227-A It a kind of preparation of bimetallic schiff bases Mo complex and its is applied in catalyzing expoxidation of olefines 福州大学 2019-07-23 CN claimed
CN-106198787-B The purposes and detection method of 3,3 '-diaminobenzidines and its quinoxaline analog in biacetyl context of detection 西北大学 2019-04-05 CN claimed
CN-105699471-B A method of two kinds of substances are detected simultaneously 中国科学院烟台海岸带研究所 2019-02-26 CN claimed
CN-108484909-A A kind of fluorine graphene oxide/composite polyimide material and its preparation method and application 中国科学院福建物质结构研究所 2018-09-04 CN claimed
CN-107057569-A A kind of nano inorganic silicate zinc-rich composite anticorrosion coating and preparation method thereof 惠州市博罗至诚化工有限公司 2017-08-18 CN claimed
CN-107057570-A A kind of superhigh temperature resistant heat-insulating anti-corrosive coating and preparation method thereof 惠州市博罗至诚化工有限公司 2017-08-18 CN claimed
CN-107012008-A It is a kind of for foam type engine cleaning agent that can directly discharge of pressurized tank and preparation method thereof 沈阳市沈北新区朗润汽车养护用品厂 2017-08-04 CN claimed
CN-106904907-A A kind of environment-friendly solvent-free mineral coating for wall plastering and preparation method thereof 惠州市博罗至诚化工有限公司 2017-06-30 CN claimed
CN-106898802-A A kind of high-performing car hydrogen fuel cell composite nano-powder material and preparation method thereof 广州市新稀复合材料有限公司 2017-06-27 CN claimed
CN-105237785-A Preparation method for polyimide thin film UNIV NANJING SCIENCE & TECH 2016-01-13 CN claimed
CN-103435804-A Polybenzimidazole with side groups and ether bonds and preparation method and application thereof UNIV JILIN 2013-12-11 CN claimed
CN-101900724-B Method for identifying cordyceps sinensis phorozoon by using immunohistochemistry UNIV HEBEI ENGINEERING 2013-10-16 CN claimed
CN-103293310-A Kit for detecting premature rupture of fetal membranes ORIGISSAY DIAGNOSTICS LTD 2013-09-11 CN claimed
CN-103076453-A P16 immune cell chemical reagent kit and polypeptide sequence in preparing same HE YIFENG 2013-05-01 CN claimed
CN-102268134-A Preparation method for polyimide/graphene nanocomposite material 2011-12-07 CN claimed
CN-102175673-A Method for detecting total selenium content ANHUI TIGER BIOTECHNOLOGY CO LTD 2011-09-07 CN claimed
CN-101280335-A Screening and identifying method for cow mycobacteria immunogenic secreted protein UNIV SHANGHAI JIAOTONG (CN) 2008-10-08 CN claimed
CN-101078730-A Enzyme labeled chip method capable of in situ detecting multiple ordinary small molecule drugs HONGWU DU (CN) 2007-11-28 CN claimed
US-4717764-A Two stage melt polymerization process for making polymers containing aromatic amide groups CELANESE CORPORATION (US) 1988-01-05 US claimed