SCHEMBL21297244

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15829849	0.83	CYP11B1 (0.51)	MAPTCYP11B1CYP11B2RIPK2PRMT5
	SCHEMBL17560098	0.81	MAPT (0.48)	MAPTCYP11B1CYP11B2RIPK2ALDH1A1
	SCHEMBL17560212	0.81	KDM4E (0.50)	MAPTCYP11B1CYP11B2RIPK2ALDH1A1
	SCHEMBL17303754	0.81	KDM4E (0.58)	MAPTALDH1A1KDM4EHTTUSP2
	SCHEMBL16217400	0.80	CYP11B1 (0.48)	MAPTCYP11B1CYP11B2RIPK2ALDH1A1
	SCHEMBL17308595	0.80	MEN1 (0.45)	CYP11B1CYP11B2NPSR1MEN1GAA
	SCHEMBL18466156	0.80	CYP11B1 (0.48)	MAPTCYP11B1CYP11B2RIPK2ALDH1A1
	SCHEMBL22678655	0.78	CYP11B1 (0.47)	MAPTCYP11B1CYP11B2RIPK2ALDH1A1
	SCHEMBL20044931	0.78	CYP11B1 (0.47)	MAPTCYP11B1CYP11B2RIPK2ALDH1A1
	SCHEMBL23684182	0.77	ALDH1A1 (0.46)	MAPTCYP11B1CYP11B2RIPK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.