Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24703969 | 0.82 | KDM4E (0.34) | KDM4EALDH1A1FOLH1 | |
| SCHEMBL24678191 | 0.82 | KDM4E (0.34) | KDM4EALDH1A1FOLH1 | |
| SCHEMBL11956479 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1 | |
| SCHEMBL25132732 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1 | |
| SCHEMBL16248631 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1 | |
| SCHEMBL17662433 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1 | |
| SCHEMBL18513363 | 0.80 | SIRT5 (0.34) | FOLH1 | |
| SCHEMBL22375468 | 0.77 | — | — | |
| SCHEMBL24468878 | 0.76 | — | — | |
| SCHEMBL16248528 | 0.75 | KDM4E (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392428-B2 | GLP-1 derivatives and uses thereof | NOVO NORDISK A/S (DK) | 2019-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392428-B2 | GLP-1 derivatives and uses thereof | GLP1R, GIPR, VIP | KDM4E 2698/4885ALDH1A1 1733/4885FOLH1 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.