⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22375471 | 0.84 | FOLH1 (0.32) | — | |
| SCHEMBL24012407 | 0.81 | CNR2 (0.32) | — | |
| SCHEMBL20980231 | 0.80 | ADRB2 (0.32) | — | |
| SCHEMBL22375470 | 0.79 | CNR2 (0.32) | — | |
| SCHEMBL21297373 | 0.77 | KDM4E (0.32) | — | |
| SCHEMBL24468878 | 0.71 | — | — | |
| SCHEMBL20980230 | 0.69 | ALB (0.38) | — | |
| SCHEMBL24012449 | 0.69 | FOLH1 (0.30) | — | |
| SCHEMBL15706851 | 0.68 | FOLH1 (0.32) | — | |
| SCHEMBL13448062 | 0.68 | FOLH1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268898-A1 | GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF | IONIS PHARMACEUTICALS, INC. | 2020-08-27 | — | — | US | disclosed |