Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002073 | 0.88 | MEN1 (0.54) | LTA4HALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23690572 | 0.85 | LTA4H (0.58) | LTA4HTAAR1XIAPMEN1KMT2A | |
| SCHEMBL24279700 | 0.84 | ALDH1A1 (0.47) | LTA4HALDH1A1XIAPMEN1KMT2A | |
| SCHEMBL22154229 | 0.83 | NPC1 (0.48) | LTA4HALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL26351482 | 0.83 | NPC1 (0.48) | LTA4HALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13411546 | 0.81 | ALDH1A1 (0.51) | LTA4HALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25854487 | 0.81 | LTA4H (0.43) | LTA4HTAAR1MEN1KMT2ALMNA | |
| SCHEMBL20283600 | 0.81 | KMT2A (0.46) | LTA4HALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL24753902 | 0.81 | LTA4H (0.59) | LTA4HTAAR1XIAPMEN1KMT2A | |
| SCHEMBL22295788 | 0.81 | LTA4H (0.59) | LTA4HTAAR1XIAPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392421-B2 | Cytotoxic peptides and conjugates thereof | NOVARTIS AG (CH) | 2019-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392421-B2 | Cytotoxic peptides and conjugates thereof | CD47, NGLY1, VIP | LTA4H 3448/4885TAAR1 4744/4885ALDH1A1 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.