Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 1.00 |
| ▸ | MAOB | P27338 | 11/20 | 1.00 |
| ▸ | PRKCI | P41743 | 1/20 | 1.00 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.74 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825921 | 0.96 | MAOA (0.92) | MAOAMAOBPRKCIHSD17B1PBRM1 | |
| SCHEMBL389710 | 0.88 | MAOB (0.78) | MAOAMAOBPRKCIHSD17B1PBRM1 | |
| SCHEMBL27323917 | 0.87 | MAOB (0.77) | MAOAMAOBPRKCIHSD17B1PBRM1 | |
| SCHEMBL4090561 | 0.85 | HSD17B1 (1.00) | MAOAMAOBPRKCIHSD17B1PBRM1 | |
| SCHEMBL385554 | 0.84 | PBRM1 (0.78) | MAOAMAOBPRKCIHSD17B1PBRM1 | |
| SCHEMBL29983572 | 0.84 | PBRM1 (0.78) | MAOAMAOBPRKCIHSD17B1PBRM1 | |
| SCHEMBL5203864 | 0.82 | MAOB (0.69) | MAOAMAOBPRKCIHSD17B1PBRM1 | |
| SCHEMBL3021186 | 0.81 | HSD17B1 (0.74) | MAOAMAOBPRKCIHSD17B1BAZ2B | |
| Hydrochloric Acid SCHEMBL6531236 | 0.81 | PBRM1 (0.72) | MAOAMAOBPRKCIHSD17B1PBRM1 | |
| SCHEMBL21300548 | 0.80 | MAOB (0.64) | MAOAMAOBPRKCIMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1085 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088765-B | Method for preparing 6-methoxy-1-tetralone by utilizing microchannel reactor | 烟台舜康生物科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-115073435-B | Near infrared fluorescent probe for detecting hydrogen sulfide and preparation method thereof | 西北大学 | 2023-11-28 | — | — | CN | claimed |
| CN-117088765-A | Method for preparing 6-methoxy-1-tetralone by utilizing microchannel reactor | 烟台舜康生物科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-114479104-B | Reagent and detection method for detecting Pi and o-phenylenediamine based on visual tandem | 辽宁大学 | 2023-05-30 | — | — | CN | claimed |
| CN-115785139-A | Near-infrared fluorescent probe for hydrogen peroxide imaging and preparation method and application thereof | 山东省华泰营养健康产业技术研究院有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115073435-A | Near-infrared fluorescent probe for detecting hydrogen sulfide and preparation method thereof | 西北大学 | 2022-09-20 | — | — | CN | claimed |
| US-20220274955-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS, INC. | 2022-09-01 | — | — | US | claimed |
| CN-110204536-B | Fluorescent probe for distinguishing and detecting Cys/Hcy and GSH and preparation method thereof | 山西大学 | 2021-07-27 | — | — | CN | claimed |
| CN-112920157-A | Benzene coupling benzopyran derivative and synthetic method and application thereof | 山西大学 | 2021-06-08 | — | — | CN | claimed |
| CN-111718319-A | Fluorescent probe for distinguishing and detecting mercaptan and monitoring Cys/GSH metabolism and preparation method thereof | 山西大学 | 2020-09-29 | — | — | CN | claimed |
| CN-109897627-A | A kind of near infrared fluorescent probe and its preparation method and application of quick detection ONOO- | 山西大学 | 2019-06-18 | — | — | CN | claimed |
| EP-2194035-B1 | Hydroxytetralones | SALTIGO GMBH (DE) | 2011-11-02 | — | — | EP | claimed |
| EP-1257812-B1 | METHOD FOR THE PHOTOMETRIC DETECTION OF IONS USING CAPILLARY ELECTROPHORESIS PROBES, METHOD FOR THE MANUFACTURING AND USAGE OF SAID PROBES | ELECTRIC POWER RES INST (US) | 2009-04-01 | — | — | EP | claimed |
| EP-1257812-A4 | CAPILLARY ELECTROPHORESIS PROBES AND METHOD | ELECTRIC POWER RES INST (US) | 2006-06-07 | — | — | EP | claimed |
| US-6953520-B2 | Capillary electrophoresis probes and method | ELECTRIC POWER RESEARCH INSTITUTE, INC. (US) | 2005-10-11 | — | — | US | claimed |
| EP-1257812-A1 | CAPILLARY ELECTROPHORESIS PROBES AND METHOD | THE ELECTRIC POWER RESEARCH INSTITUTE (US) | 2002-11-20 | — | — | EP | claimed |
| US-20020092768-A1 | Capillary electrophoresis probes and method | ELECTRIC POWER RESEARCH INSTITUTE, INC. | 2002-07-18 | — | — | US | claimed |
| WO-2001040785-A1 | CAPILLARY ELECTROPHORESIS PROBES AND METHOD | ELECTRIC POWER RESEARCH INSTITUTE (US) | 2001-06-07 | — | — | WO | claimed |
| CN-117777152-B | Mercury ion anthocyanin fluorescent probe, preparation method and application thereof in detection of traditional Chinese medicine plants | ANHUI UNIVERSITY OF CHINESE MEDICINE (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-3761497-A | METHOD OF PRODUCING RACEMIC ESTRADIOL-3,17{62 | SEREBRYAKOVA T | 1973-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274955-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | MDM2, CRBN, VHL | MAOA 3116/4885MAOB 3417/4885PRKCI 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.