Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17103193 | 0.90 | RORC (0.57) | RORCKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL17103191 | 0.89 | RORC (0.58) | RORCKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL17103330 | 0.89 | RORC (0.68) | RORCKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL17103219 | 0.85 | KMT2A (0.52) | RORCKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL17103194 | 0.85 | RORC (0.58) | RORCKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL2954791 | 0.84 | ALDH1A1 (0.65) | RORCKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL29397255 | 0.84 | ALDH1A1 (0.65) | RORCKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL17103179 | 0.83 | RORC (0.56) | RORCKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL17103212 | 0.83 | RORC (0.55) | RORCKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL13265946 | 0.78 | TSHR (0.62) | RORCKMT2AMEN1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2924021-B1 | ANTI-HIV COMPOUND AND PREPARATION METHOD AND USE THEREOF | UNIV SICHUAN (CN) | 2019-08-28 | — | — | EP | disclosed |