Sugi Predict

Sugi Predict / Compounds / SCHEMBL29397255

SCHEMBL29397255

SCHEMBL29397255

COc1ccccc1NC(=O)c1ccccc1Sc1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.65
▸ PKM P14618 2/20 0.65
▸ CRHBP P24387 1/20 0.65
▸ CRHR2 Q13324 1/20 0.65
▸ KMT2A Q03164 4/20 0.64
▸ MEN1 O00255 2/20 0.64
▸ MAPT P10636 3/20 0.61
▸ TDP1 Q9NUW8 1/20 0.61
▸ TSHR P16473 2/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ HSD17B10 Q99714 1/20 0.61
▸ RORC P51449 1/20 0.61
▸ KCNMA1 Q12791 2/20 0.56
▸ MAOB P27338 1/20 0.54
▸ METAP2 P50579 1/20 0.53
▸ LMNA P02545 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2954791 1.00 ALDH1A1 (0.65) ALDH1A1PKMCRHBPCRHR2KMT2A
SCHEMBL17103330 0.91 RORC (0.68) ALDH1A1PKMCRHBPCRHR2KMT2A
SCHEMBL13265946 0.91 TSHR (0.62) ALDH1A1PKMCRHBPCRHR2KMT2A
SCHEMBL13265768 0.90 PKM (0.63) ALDH1A1PKMCRHBPCRHR2KMT2A
SCHEMBL17103194 0.88 RORC (0.58) ALDH1A1PKMCRHBPCRHR2KMT2A
SCHEMBL17103193 0.87 RORC (0.57) ALDH1A1PKMCRHBPCRHR2KMT2A
SCHEMBL18584852 0.87 MAPT (0.62) ALDH1A1PKMCRHBPCRHR2KMT2A
SCHEMBL18585211 0.87 ALDH1A1 (0.62) ALDH1A1PKMCRHBPCRHR2KMT2A
SCHEMBL17103179 0.86 RORC (0.56) ALDH1A1PKMCRHBPCRHR2KMT2A
SCHEMBL17103191 0.86 RORC (0.58) ALDH1A1PKMCRHBPCRHR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421255-B2 Luminescence device and polycyclic compound for luminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2025-09-23 — — US claimed
CN-114886901-A Application of betulinic acid and RN-18 in preparation of medicine for resisting porcine epidemic diarrhea virus 山东省农业科学院家禽研究所（山东省无特定病原鸡研究中心） 2022-08-12 — — CN claimed
US-12636279-B2 Choline salt forms of an HIV capsid inhibitor GILEAD SCIENCES, INC. (US) 2026-05-26 — — US disclosed
CN-122055369-A Bridged tricyclic carbamoyl pyridone compounds and uses thereof 吉利德科学公司 2026-05-15 — — CN disclosed
CN-122036801-A Crystalline forms of tenofovir alafenamide 吉利德科学公司 2026-05-15 — — CN disclosed
CN-122055373-A Bridged tricyclic carbamoyl pyridone compounds and uses thereof 吉利德科学公司 2026-05-15 — — CN disclosed
US-20260132139-A1 HIV INHIBITOR COMPOUNDS GILEAD SCIENCES INC (US) 2026-05-14 — — US disclosed
WO-2026090160-A2 CD4-TARGETED IL-15 MOLECULES AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2026-04-30 — — WO disclosed
US-20260109746-A1 CD4-TARGETED IL-15 MOLECULES AND METHODS OF USE GILEAD SCIENCES INC (US) 2026-04-23 — — US disclosed
EP-4719602-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-04-08 — — EP disclosed
EP-4720056-A1 SOLID FORMS OF COMPOUNDS USEFUL IN THE TREATMENT OF HIV GILEAD SCIENCES, INC. (US) 2026-04-08 — — EP disclosed
CN-114245807-A FLT3L-FC fusion proteins and methods of use 吉利德科学公司 2022-03-25 — — CN disclosed
US-11267799-B2 Solid forms of an HIV capsid inhibitor GILEAD SCIENCES, INC. (US) 2022-03-08 — — US disclosed
US-11267801-B2 Therapeutic compounds GILEAD SCIENCES, INC. (US) 2022-03-08 — — US disclosed
US-11266638-B2 Choline salt forms of an HIV capsid inhibitor GILEAD SCIENCES, INC. (US) 2022-03-08 — — US disclosed
WO-2022046644-A1 MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2022-03-03 — — WO disclosed
EP-3960740-A1 CRYSTALLINE FORMS OF ETHYL ((S)-((((2R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-FLUORO-2,5-DIHYDROFURAN-2-YL)OXY)METHYL)(PHENOXY)PHOSPHORYL)-L-ALANINATE (GS-9131) VANILLATE FOR TREATING VIRAL INFECTIONS Gilead Sciences, Inc. (US) 2022-03-02 — — EP disclosed
EP-3960735-A1 QUINAZOLINE DERIVATIVES USED TO TREAT HIV Gilead Sciences, Inc. (US) 2022-03-02 — — EP disclosed
EP-3955921-A1 2-IMINO-5-OXO-IMIDAZOLIDINE INHIBITORS OF HIV PROTEASE GILEAD SCIENCES, INC. (US) 2022-02-23 — — EP disclosed
US-20220049021-A1 FLT3L-Fc FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES, INC. 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11267801-B2 Therapeutic compounds NPC1, CCR5, FURIN ALDH1A1 742/4885PKM 1699/4885CRHBP 4094/4885
US-12636279-B2 Choline salt forms of an HIV capsid inhibitor CHKA, SLC5A7, SLC44A1 ALDH1A1 2774/4885PKM 4656/4885CRHBP 4645/4885
US-12421255-B2 Luminescence device and polycyclic compound for luminescence device LUC7L2, BMI1, SIRT7 ALDH1A1 2075/4885PKM 3347/4885CRHBP 2655/4885
US-11266638-B2 Choline salt forms of an HIV capsid inhibitor CHKA, SLC44A1, SLC5A7 ALDH1A1 1677/4885PKM 4450/4885CRHBP 4596/4885
US-20260132139-A1 HIV INHIBITOR COMPOUNDS SLC11A2, SLC6A15, NHERF1 ALDH1A1 2353/4885PKM 1376/4885CRHBP 2753/4885
US-20260109746-A1 CD4-TARGETED IL-15 MOLECULES AND METHODS OF USE IL15, IL15RA, CD4 ALDH1A1 4818/4885PKM 3810/4885CRHBP 2062/4885
US-11267799-B2 Solid forms of an HIV capsid inhibitor ZC3HAV1, ZC3HAV1L, PRNP ALDH1A1 2344/4885PKM 4031/4885CRHBP 4146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback