Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21310548 | 0.88 | NPC1 (0.36) | ALDH1A1MAPK1CA2PDK2CA1 | |
| SCHEMBL21310691 | 0.86 | GUSB (0.32) | ALDH1A1MAPK1CA12MAPTKMT2A | |
| SCHEMBL21310626 | 0.82 | CYP2A6 (0.36) | ALDH1A1MAPK1MEN1MAPTKMT2A | |
| SCHEMBL21310602 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MAPK1CA2PDK2CA1 | |
| SCHEMBL26017258 | 0.78 | ADORA2A (0.40) | ALDH1A1PDK2GPR3MEN1POLB | |
| SCHEMBL21310577 | 0.77 | ALDH1A1 (0.33) | ALDH1A1MAPK1CA2PDK2CA1 | |
| SCHEMBL19734148 | 0.77 | GPR3 (0.48) | ALDH1A1CA2CA1CA7CA9 | |
| SCHEMBL20091624 | 0.75 | GPR3 (0.46) | ALDH1A1MAPK1CA2CA1CA7 | |
| SCHEMBL21310579 | 0.75 | CYP2A6 (0.39) | ALDH1A1POLBKMT2A | |
| SCHEMBL21310688 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MAPK1CA2PDK2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
| US-20190263841-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263841-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, EED, FES | ALDH1A1 636/4885MAPK1 2169/4885CA2 4298/4885 |
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | ALDH1A1 752/4885MAPK1 3471/4885CA2 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.