Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12992529 | 0.89 | MAPT (0.40) | KDM4EMAPTTP53HPGDALOX15 | |
| SCHEMBL24672211 | 0.81 | HSD17B10 (0.53) | KDM4EMAPTTP53HPGDALOX15 | |
| SCHEMBL18904001 | 0.81 | ALDH1A1 (0.40) | MAPTHPGDALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL14420505 | 0.81 | ALDH1A1 (0.40) | MAPTHPGDALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL19170362 | 0.81 | ALDH1A1 (0.45) | MAPTHPGDALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL19538018 | 0.80 | PTGER4 (0.34) | AKR1C3SIRT2 | |
| SCHEMBL19529079 | 0.79 | — | — | |
| SCHEMBL26012679 | 0.79 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL12193227 | 0.77 | MEN1 (0.44) | KDM4EMAPTTP53HPGDALOX15 | |
| SCHEMBL24783205 | 0.76 | ALOX5 (0.35) | KDM4EMAPTTP53HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190263841-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263841-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, EED, FES | KDM4E 2467/4885MAPT 2721/4885TP53 3972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.