SCHEMBL24672211

SCHEMBL24672211

C1=CC(c2ccc(Nc3cccc4ccccc34)cc2)=CCC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.53
ALDH1A1 P00352 3/20 0.53
HPGD P15428 3/20 0.53
TP53 P04637 2/20 0.53
CYP3A4 P08684 2/20 0.53
CDC25B P30305 2/20 0.53
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
ATM Q13315 1/20 0.53
RAB9A P51151 4/20 0.48
FADS1 O60427 1/20 0.46
KDM4E B2RXH2 4/20 0.41
GAA P10253 4/20 0.41
MAPT P10636 4/20 0.41
MEN1 O00255 1/20 0.41
GLA P06280 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21310620 0.81 KDM4E (0.31) HSD17B10HPGDTP53ALOX15KDM4E
SCHEMBL24783205 0.81 ALOX5 (0.35) HSD17B10ALDH1A1HPGDTP53CYP3A4
SCHEMBL12193227 0.80 MEN1 (0.44) HSD17B10ALDH1A1HPGDTP53CYP3A4
SCHEMBL29521400 0.78 HSD17B10 (0.77) HSD17B10ALDH1A1HPGDTP53CYP3A4
SCHEMBL74528 0.78 HSD17B10 (0.77) HSD17B10ALDH1A1HPGDTP53CYP3A4
SCHEMBL19170362 0.77 ALDH1A1 (0.45) HSD17B10ALDH1A1HPGDCYP3A4ALOX15
SCHEMBL18904001 0.77 ALDH1A1 (0.40) HSD17B10ALDH1A1HPGDCYP3A4ALOX15
SCHEMBL14420505 0.77 ALDH1A1 (0.40) HSD17B10ALDH1A1HPGDCYP3A4ALOX15
SCHEMBL21992220 0.77 ALDH1A1 (0.53) HSD17B10ALDH1A1HPGDCYP3A4RAB9A
SCHEMBL14420501 0.77 KDM1A (0.34) HSD17B10ALDH1A1HPGDTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022250244-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2022-12-01 WO disclosed