SCHEMBL21311200

SCHEMBL21311200

Cc1ccc2c3c(C)cccc3n(CCNCC3OCC(O)(n4cnc5c(N)ncnc54)C3O)c2c1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NNMT P40261 1/20 0.34
▸ PIK3CD O00329 9/20 0.33
▸ GMPS P49915 1/20 0.33
▸ SLC28A1 O00337 1/20 0.33
▸ PNMT P11086 2/20 0.32
▸ SLC28A2 O43868 1/20 0.32
▸ ADORA3 P0DMS8 1/20 0.31
▸ ADORA2A P29274 1/20 0.31
▸ CARM1 Q86X55 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21311198 0.92 NNMT (0.34) NNMTGMPSSLC28A1PNMTSLC28A2
SCHEMBL20097182 0.91 GMPS (0.35) NNMTGMPSSLC28A1PNMTADORA3
SCHEMBL20096951 0.91 DOT1L (0.36) NNMTPIK3CD
SCHEMBL21311199 0.89 GMPS (0.35) NNMTGMPSSLC28A1PNMTADORA3
SCHEMBL21311196 0.87 DOT1L (0.34) NNMTGMPSSLC28A1PNMTADORA3
SCHEMBL21311205 0.86 GMPS (0.33) GMPSSLC28A1ADORA3ADORA2A
SCHEMBL21311192 0.84 DOT1L (0.37) GMPSSLC28A1PNMTADORA3ADORA2A
SCHEMBL21311204 0.84 DOT1L (0.34) NNMTGMPSSLC28A1PNMTADORA3
SCHEMBL21311197 0.83 DOT1L (0.35) NNMT
SCHEMBL21311401 0.83 DOT1L (0.36) GMPSSLC28A1ADORA3ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-08-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS POLRMT, EIF2AK2, NSUN3 NNMT 865/4885PIK3CD 3155/4885GMPS 847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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