Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 2/20 | 0.32 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | GMPS | P49915 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311198 | 0.93 | NNMT (0.34) | DOT1LNNMTSLC28A1CHKALMNA | |
| SCHEMBL21311197 | 0.90 | DOT1L (0.35) | DOT1LNNMTCHKA | |
| SCHEMBL21311192 | 0.90 | DOT1L (0.37) | DOT1LSLC28A1PNMTAHCYGMPS | |
| SCHEMBL20097182 | 0.85 | GMPS (0.35) | DOT1LNNMTSLC28A1PNMTAHCY | |
| SCHEMBL21311196 | 0.85 | DOT1L (0.34) | DOT1LNNMTSLC28A1PNMTAHCY | |
| SCHEMBL21311211 | 0.85 | PNMT (0.36) | DOT1LNNMTPNMTAHCYGMPS | |
| SCHEMBL21311200 | 0.84 | NNMT (0.34) | NNMTSLC28A1PNMTGMPSADORA3 | |
| SCHEMBL21311212 | 0.83 | DOT1L (0.35) | DOT1LNNMTSLC28A1PNMTAHCY | |
| SCHEMBL21311390 | 0.81 | DOT1L (0.34) | DOT1LNNMTSLC28A1PNMTAHCY | |
| SCHEMBL21311209 | 0.81 | DOT1L (0.38) | DOT1LPNMTGMPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | DOT1L 2274/4885NNMT 865/4885SLC28A1 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.