Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066924 | 0.90 | PAX8 (0.45) | NOS2ALDH1A1SMN1; SMN2PSMB5PAX8 | |
| SCHEMBL17693759 | 0.90 | PAX8 (0.46) | NOS2ALDH1A1PSMB5PAX8HSP90AA1 | |
| SCHEMBL22221603 | 0.90 | PAX8 (0.46) | NOS2ALDH1A1PSMB5PAX8HSP90AA1 | |
| SCHEMBL21303829 | 0.90 | PAX8 (0.46) | NOS2ALDH1A1PSMB5PAX8HSP90AA1 | |
| SCHEMBL23334307 | 0.89 | PAX8 (0.44) | NOS2ALDH1A1PSMB5PAX8HSP90AA1 | |
| SCHEMBL17693744 | 0.89 | NOS2 (0.48) | NOS2PSMB5PAX8HSP90AA1CARM1 | |
| SCHEMBL24253325 | 0.89 | PSMB5 (0.46) | NOS2ALDH1A1PSMB5PAX8HSP90AA1 | |
| SCHEMBL24253327 | 0.89 | PSMB5 (0.46) | NOS2ALDH1A1PSMB5PAX8HSP90AA1 | |
| SCHEMBL23334290 | 0.89 | PSMB5 (0.46) | NOS2ALDH1A1PSMB5PAX8HSP90AA1 | |
| SCHEMBL21303814 | 0.88 | PAX8 (0.46) | NOS2ALDH1A1SMN1; SMN2PSMB5PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019165216-A1 | SMALL MOLECULES THAT BLOCK PROTEASOME-ASSOCIATED UBIQUITIN RECEPTOR RPN13 FUNCTION AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-08-29 | — | — | WO | disclosed |