Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22879310 | 0.78 | LMNA (0.45) | PPIAMEN1KMT2ANOS1PARP1 | |
| SCHEMBL3290310 | 0.77 | MEN1 (0.56) | PPIAMEN1KMT2ANOS1PARP1 | |
| SCHEMBL22879514 | 0.76 | ANPEP (0.45) | PPIAMEN1KMT2APARP1 | |
| SCHEMBL22879359 | 0.76 | PARP1 (0.42) | PPIAMEN1KMT2APARP1BCHE | |
| SCHEMBL12813351 | 0.75 | PPIA (0.47) | PPIAMEN1KMT2AESR1ESR2 | |
| SCHEMBL1504379 | 0.75 | NOS1 (0.42) | PPIAMEN1KMT2AESR1ESR2 | |
| SCHEMBL8894478 | 0.75 | PPIA (0.40) | PPIAMEN1KMT2AESR1ESR2 | |
| SCHEMBL7544039 | 0.75 | NOS1 (0.42) | PPIAMEN1KMT2AESR1ESR2 | |
| SCHEMBL22879372 | 0.75 | CYP2C9 (0.40) | PPIAMEN1KMT2AESR1ESR2 | |
| SCHEMBL21311754 | 0.75 | PARP1 (0.35) | PPIAMEN1KMT2ANOS1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |
| EP-3760620-A1 | RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USAGE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| WO-2019161781-A1 | RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USAGE THEREOF | 北京泰德制药股份有限公司 | 2019-08-29 | — | — | WO | disclosed |