Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 8/20 | 0.68 |
| ▸ | KDR | P35968 | 6/20 | 0.59 |
| ▸ | FLT1 | P17948 | 5/20 | 0.59 |
| ▸ | FLT4 | P35916 | 5/20 | 0.59 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134239 | 0.91 | KDR (0.66) | VCPKDRFLT1FLT4SIRT7 | |
| SCHEMBL21311878 | 0.90 | VCP (0.64) | VCPKDRFLT1FLT4SIRT7 | |
| SCHEMBL14058473 | 0.87 | KDR (0.67) | VCPKDRFLT1FLT4SIRT7 | |
| SCHEMBL14057525 | 0.87 | TRPV1 (0.66) | VCPKDRFLT1FLT4SIRT7 | |
| SCHEMBL21311881 | 0.86 | VCP (0.78) | VCPKDRFLT1FLT4HSD17B1 | |
| SCHEMBL21311885 | 0.85 | VCP (0.85) | VCPKDRFLT1FLT4SIRT7 | |
| SCHEMBL5184578 | 0.83 | KDR (0.72) | VCPKDRFLT1FLT4HSD17B1 | |
| SCHEMBL14058062 | 0.81 | IMPDH2 (0.66) | VCPKDRFLT1FLT4SIRT7 | |
| SCHEMBL1909825 | 0.81 | KDR (0.49) | VCPKDRFLT1FLT4SIRT7 | |
| SCHEMBL13612916 | 0.79 | VCP (0.50) | VCPKDRFLT1FLT4SIRT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019162911-A1 | FNEW ACTIVATORS OF SIRT1 ENZYME FOR THE TREATMENT OF CARDIOVASCULAR AND CARDIOMETABOLIC PATHOLOGIES | UNIVERSITA' DI PISA (IT) | 2019-08-29 | — | — | WO | disclosed |