Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21313171 | 0.88 | ADORA2A (0.47) | ADORA2AADORA1ALDH1A1ATMMAPT | |
| SCHEMBL21313144 | 0.88 | ADORA2A (0.62) | ADORA2AADORA1ALDH1A1CYP2D6ATM | |
| SCHEMBL21313193 | 0.86 | ADORA2A (0.62) | ADORA2AADORA1ALDH1A1CYP2D6ATM | |
| SCHEMBL21313200 | 0.86 | DHFR (0.44) | ADORA2AALDH1A1CYP2D6NPSR1KMT2A | |
| SCHEMBL21313252 | 0.84 | ADORA2A (0.53) | ADORA2AADORA1ALDH1A1DPP4KMT2A | |
| SCHEMBL21313259 | 0.83 | ADORA2A (0.45) | ADORA2AADORA1ALDH1A1MAPTKMT2A | |
| SCHEMBL21313166 | 0.83 | ADORA2A (0.55) | ADORA2AADORA1DPP4KMT2A | |
| SCHEMBL21313256 | 0.82 | ADORA2A (0.56) | ADORA2AADORA1ALDH1A1CYP2D6ATM | |
| SCHEMBL21313253 | 0.82 | ADORA2A (0.56) | ADORA2AADORA1ALDH1A1CYP2D6ATM | |
| SCHEMBL21313197 | 0.78 | CYP11B2 (0.54) | ADORA2AADORA1ALDH1A1CYP2D6ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3195867-B1 | PYRIMIDINE COMPOUNDS INHIBITING THE FORMATION OF NITRIC OXIDE AND PROSTAGLANDIN E2, METHOD OF PRODUCTION THEREOF AND USE THEREOF | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CR V V I (CZ) | 2019-09-04 | — | — | EP | claimed |