Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21320484 | 0.94 | PPARG (0.31) | PPARGPPARAAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL21320330 | 0.89 | L3MBTL1 (0.34) | AKR1C4AKR1C3AKR1C2AKR1C1RXRA | |
| SCHEMBL21320465 | 0.87 | PTGER4 (0.34) | AKR1C4AKR1C3AKR1C2AKR1C1RXRA | |
| SCHEMBL26057050 | 0.87 | KDM4E (0.34) | RXRARXRBPTPN1 | |
| SCHEMBL21319924 | 0.86 | GRIN2B (0.34) | RXRARXRB | |
| SCHEMBL21740444 | 0.85 | MMP12 (0.31) | — | |
| SCHEMBL21319941 | 0.84 | GRIN2B (0.34) | — | |
| SCHEMBL21319923 | 0.84 | PTGER4 (0.33) | RXRARXRB | |
| SCHEMBL21668697 | 0.84 | TDP2 (0.30) | — | |
| SCHEMBL26056238 | 0.84 | MMP12 (0.33) | AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3015465-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2019-09-04 | — | — | EP | disclosed |