Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | CALCA | P06881 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17112554 | 0.84 | OPRK1 (0.33) | CHRNA7LMNARECQL | |
| SCHEMBL17112622 | 0.79 | KCNK3 (0.42) | — | |
| SCHEMBL17112620 | 0.79 | KCNK3 (0.42) | — | |
| SCHEMBL16963764 | 0.74 | KCNH2 (0.40) | HRH4KCNH2 | |
| SCHEMBL21321436 | 0.72 | TLR9 (0.48) | HRH4HRH3 | |
| SCHEMBL21322968 | 0.72 | TLR9 (0.48) | HRH4HRH3 | |
| SCHEMBL3698590 | 0.71 | TLR8 (0.48) | CHKA | |
| SCHEMBL241363 | 0.70 | TP53 (0.37) | LMNA | |
| SCHEMBL501616 | 0.69 | MEN1 (0.39) | — | |
| SCHEMBL243112 | 0.69 | GABRA1 (0.40) | LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122750-B1 | BICYCLIC COMPOUNDS AS AUTOTAXIN (ATX) AND LYSOPHOSPHATIDIC ACID (LPA) PRODUCTION INHIBITORS | HOFFMANN LA ROCHE (CH) | 2019-09-04 | — | — | EP | disclosed |