Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SDCBP | O00560 | 1/20 | 0.36 |
| ▸ | SDC2 | P34741 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10244720 | 0.76 | CYP2A6 (0.45) | SDHBPGRNR3C1NR3C2AR | |
| SCHEMBL5438422 | 0.73 | SDHB (0.48) | SDHBL3MBTL1MAPTCREBBPCYP11B2 | |
| SCHEMBL21264620 | 0.72 | L3MBTL1 (0.45) | SDHBL3MBTL1CREBBPCYP11B2 | |
| SCHEMBL18361192 | 0.69 | PTGDR2 (0.46) | PGRGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL14240796 | 0.68 | RAB9A (0.49) | PGRL3MBTL1MAPTKDM1A | |
| SCHEMBL15537950 | 0.68 | GRM5 (0.42) | PGRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10061105 | 0.68 | HDAC3 (0.53) | L3MBTL1POLBMAPTCASP3PTGDR2 | |
| SCHEMBL16343938 | 0.67 | PTGDR2 (0.49) | PGRL3MBTL1GABRG2GABRB3GABRA5 | |
| SCHEMBL29788195 | 0.67 | PTGDR2 (0.49) | PGRL3MBTL1GABRG2GABRB3GABRA5 | |
| SCHEMBL2037109 | 0.66 | SLC22A12 (0.53) | NR3C2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533787-B1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2020-09-30 | — | — | EP | disclosed |
| EP-3533787-A1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | Fujian Cosunter Pharmaceutical Co., Ltd. (CN) | 2019-09-04 | — | — | EP | disclosed |