Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21322016 | 0.86 | EP300 (0.47) | METNQO2AKT1 | |
| SCHEMBL22309754 | 0.84 | MET (0.58) | METNQO2CXCR1APAF1CASP3 | |
| SCHEMBL31495087 | 0.83 | MET (0.57) | METNQO2CXCR1APAF1CASP3 | |
| SCHEMBL12547598 | 0.83 | MET (0.57) | METNQO2CXCR1APAF1CASP3 | |
| SCHEMBL1296276 | 0.83 | MET (0.57) | METNQO2CXCR1APAF1CASP3 | |
| SCHEMBL13449240 | 0.80 | MET (0.53) | METNQO2CXCR1HRH3ACHE | |
| SCHEMBL31495102 | 0.80 | MET (0.53) | METNQO2CXCR1HRH3ACHE | |
| SCHEMBL2223511 | 0.79 | MET (0.52) | METNQO2CXCR1HRH3EGFR | |
| SCHEMBL23344107 | 0.76 | MET (0.54) | METNQO2CXCR1L3MBTL1HRH3 | |
| SCHEMBL26792863 | 0.75 | MET (0.54) | METNQO2CXCR1APAF1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533787-B1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2020-09-30 | — | — | EP | disclosed |
| EP-3533787-A1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | Fujian Cosunter Pharmaceutical Co., Ltd. (CN) | 2019-09-04 | — | — | EP | disclosed |