Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22309794 | 0.85 | GPR119 (0.54) | — | |
| SCHEMBL13449240 | 0.84 | MET (0.53) | METNQO2CXCR1KDM1AHRH3 | |
| SCHEMBL31495102 | 0.84 | MET (0.53) | METNQO2CXCR1KDM1AHRH3 | |
| SCHEMBL1296276 | 0.83 | MET (0.57) | METNQO2CXCR1HRH3L3MBTL1 | |
| SCHEMBL2223511 | 0.83 | MET (0.52) | METNQO2CXCR1HRH3LMNA | |
| SCHEMBL22309754 | 0.82 | MET (0.58) | METNQO2CXCR1HRH3ALDH1A1 | |
| SCHEMBL26792863 | 0.81 | MET (0.54) | METNQO2CXCR1KDM1ARCOR1 | |
| SCHEMBL12547598 | 0.81 | MET (0.57) | METNQO2CXCR1HRH3L3MBTL1 | |
| SCHEMBL31495087 | 0.81 | MET (0.57) | METNQO2CXCR1HRH3L3MBTL1 | |
| SCHEMBL23344096 | 0.80 | MET (0.48) | METNQO2CXCR1KDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365532-A1 | PYRIMIDINE DERIVATIVE AND PREPARATION PROCESS AND USE THEREOF | Guangdong CS-Lewwin Drug Research Co., Ltd. (CN) | 2023-11-16 | — | — | US | disclosed |
| US-20230365532-A1 | PYRIMIDINE DERIVATIVE AND PREPARATION PROCESS AND USE THEREOF | Guangdong CS-Lewwin Drug Research Co., Ltd. (CN) | 2023-11-16 | — | — | US | disclosed |
| US-20210139464-A1 | PYRIMIDINE DERIVATIVE CONTAINING ONE DEUTERIUM ATOM AND PREPARATION PROCESS AND USE THEREOF | Guangdong CS-Lewwin Drug Research Co., Ltd. (CN) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139464-A1 | PYRIMIDINE DERIVATIVE CONTAINING ONE DEUTERIUM ATOM AND PREPARATION PROCESS AND USE THEREOF | DUT, TYMP, DCTD | MET 1807/4885NQO2 758/4885CXCR1 2177/4885 |
| US-20230365532-A1 | PYRIMIDINE DERIVATIVE AND PREPARATION PROCESS AND USE THEREOF | MTR, HCCS, MET | MET 3/4885NQO2 2197/4885CXCR1 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.