Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 12/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21322203 | 0.86 | MET (0.53) | METNQO2AKT1 | |
| SCHEMBL22310321 | 0.82 | EP300 (0.53) | EP300KDM1AMAOBSLC6A2SLC6A4 | |
| SCHEMBL31495099 | 0.78 | KDM1A (0.62) | EP300KDM1AMAOBSLC6A2SLC6A4 | |
| SCHEMBL30905863 | 0.73 | MET (0.55) | EP300KDM1AMAOBMETNQO2 | |
| SCHEMBL19267087 | 0.73 | LDHA (0.44) | EP300KDM1AMAOBMETNQO2 | |
| SCHEMBL19266925 | 0.72 | EP300 (0.37) | EP300KDM1AMAOBSLC6A2SLC6A4 | |
| SCHEMBL19266912 | 0.72 | EP300 (0.37) | EP300KDM1AMAOBSLC6A2SLC6A4 | |
| SCHEMBL21322013 | 0.72 | MET (0.49) | EP300KDM1AMAOBSLC6A2SLC6A4 | |
| SCHEMBL31690422 | 0.71 | MET (0.45) | EP300KDM1AMAOBSLC6A2SLC6A4 | |
| SCHEMBL19266882 | 0.71 | MET (0.43) | EP300KDM1AMAOBSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533787-A1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | Fujian Cosunter Pharmaceutical Co., Ltd. (CN) | 2019-09-04 | — | — | EP | disclosed |