Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21322021 | 0.91 | MET (0.47) | METNQO2SLC2A1GPR119HDAC1 | |
| SCHEMBL21264618 | 0.86 | MET (0.43) | METNQO2SLC2A1GPR119HDAC1 | |
| SCHEMBL21264886 | 0.86 | MET (0.43) | METNQO2SLC2A1GPR119HDAC1 | |
| SCHEMBL21264864 | 0.84 | MET (0.53) | METNQO2SLC2A1GPR119HDAC1 | |
| SCHEMBL22310712 | 0.84 | SLC2A1 (0.54) | METNQO2SLC2A1GPR119HDAC1 | |
| SCHEMBL12547063 | 0.83 | GPR119 (0.53) | METNQO2SLC2A1GPR119HDAC1 | |
| SCHEMBL21264617 | 0.83 | MET (0.51) | METNQO2SLC2A1GPR119HDAC1 | |
| SCHEMBL21322325 | 0.83 | MET (0.47) | METNQO2SLC2A1GPR119HDAC1 | |
| SCHEMBL12547517 | 0.83 | GPR119 (0.52) | METNQO2SLC2A1GPR119HDAC1 | |
| SCHEMBL22309725 | 0.83 | GPR119 (0.52) | METNQO2SLC2A1GPR119HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533787-B1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2020-09-30 | — | — | EP | disclosed |
| EP-3533787-A1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | Fujian Cosunter Pharmaceutical Co., Ltd. (CN) | 2019-09-04 | — | — | EP | disclosed |