Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 8/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23714114 | 0.84 | MET (0.56) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL21322269 | 0.83 | MET (0.44) | METNQO2EP300ROCK2KDM1A | |
| SCHEMBL21264819 | 0.79 | MET (0.41) | METNQO2EP300KDM1AACHE | |
| SCHEMBL21264869 | 0.78 | MET (0.60) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL21264868 | 0.75 | — | — | |
| SCHEMBL21322332 | 0.75 | MET (0.46) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL21264840 | 0.75 | MET (0.46) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL21264618 | 0.74 | MET (0.43) | METNQO2KDM1AGPR119 | |
| SCHEMBL21322013 | 0.74 | MET (0.49) | METNQO2EP300ROCK2KDM1A | |
| SCHEMBL21264847 | 0.73 | MET (0.50) | METNQO2EP300KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533787-B1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2020-09-30 | — | — | EP | disclosed |
| EP-3533787-A1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | Fujian Cosunter Pharmaceutical Co., Ltd. (CN) | 2019-09-04 | — | — | EP | disclosed |