⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21322268 | 0.75 | MET (0.41) | — | |
| SCHEMBL19806007 | 0.63 | DBH (0.43) | — | |
| SCHEMBL19806130 | 0.63 | MAPK10 (0.45) | — | |
| SCHEMBL23714114 | 0.62 | MET (0.56) | — | |
| SCHEMBL19806033 | 0.59 | IDO1 (0.33) | — | |
| SCHEMBL21322269 | 0.58 | MET (0.44) | — | |
| SCHEMBL15836994 | 0.57 | BRD4 (0.40) | — | |
| SCHEMBL18764611 | 0.56 | ALDH1A1 (0.47) | — | |
| SCHEMBL16622998 | 0.55 | TDP1 (0.57) | — | |
| SCHEMBL31222865 | 0.55 | LPL (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10501443-B2 | Pyridone compound as c-met inhibitor | FUJIAN COSUNTER PHARMACEUTICAL CO., LTD. (CN) | 2019-12-10 | — | — | US | disclosed |
| US-20190248763-A1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO., LTD. (CN) | 2019-08-15 | — | — | US | disclosed |