Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 9/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21322013 | 0.87 | MET (0.49) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL21322268 | 0.83 | MET (0.41) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL21264869 | 0.83 | MET (0.60) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL21264819 | 0.83 | MET (0.41) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL22310322 | 0.79 | MET (0.39) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL21264624 | 0.78 | MET (0.52) | METNQO2KDM1AMAOB | |
| SCHEMBL21264847 | 0.76 | MET (0.50) | METNQO2EP300KDM1A | |
| SCHEMBL30905863 | 0.76 | MET (0.55) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL22310321 | 0.75 | EP300 (0.53) | METNQO2EP300KDM1AMAOB | |
| SCHEMBL22310733 | 0.75 | MET (0.47) | METNQO2KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533787-B1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2020-09-30 | — | — | EP | disclosed |
| EP-3533787-A1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | Fujian Cosunter Pharmaceutical Co., Ltd. (CN) | 2019-09-04 | — | — | EP | disclosed |