Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19170915 | 0.87 | FURIN (0.35) | C3AR1POLB | |
| SCHEMBL21322625 | 0.84 | C3AR1 (0.32) | C3AR1POLB | |
| SCHEMBL18122899 | 0.80 | — | — | |
| SCHEMBL19170914 | 0.80 | FURIN (0.35) | POLBALB | |
| SCHEMBL21534490 | 0.78 | FURIN (0.34) | POLB | |
| SCHEMBL22767956 | 0.78 | FURIN (0.34) | POLB | |
| SCHEMBL24336901 | 0.75 | LMNA (0.35) | POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL25488906 | 0.75 | LMNA (0.35) | POLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL21534501 | 0.74 | SIRT5 (0.33) | — | |
| SCHEMBL19203577 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3273998-B1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMA (US) | 2019-09-04 | — | — | EP | disclosed |