⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213285 | 1.00 | — | — | |
| SCHEMBL214379 | 0.81 | CDK4 (0.34) | — | |
| SCHEMBL214378 | 0.81 | CDK4 (0.34) | — | |
| SCHEMBL213938 | 0.79 | CDK4 (0.33) | — | |
| SCHEMBL214345 | 0.77 | ALDH1A1 (0.42) | — | |
| SCHEMBL214346 | 0.77 | ALDH1A1 (0.42) | — | |
| SCHEMBL29769344 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL1255596 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL29769345 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL212617 | 0.75 | CDK4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| US-8541509-B2 | Polymers functionalized with protected oxime compounds | BRIDGESTONE CORPORATION (JP) | 2013-09-24 | — | — | US | disclosed |
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | disclosed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | disclosed |
| US-6020495-A | Stereoselective method for synthesizing dolaphenine | PHARM-ECO LABORATORIES, INC. (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0846107-A1 | STEREOSELECTIVE METHOD FOR SYNTHESIZING DOLAPHENINE | Pharmeco Laboratories, Inc. (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5750713-A | Stereoselective method for synthesizing dolaphenine | PHARM-ECO LABORATORIES, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1996039399-A1 | STEREOSELECTIVE METHOD FOR SYNTHESIZING DOLAPHENINE | PHARM-ECO LABORATORIES, INC. (US) | 1996-12-12 | — | — | WO | disclosed |