Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214379 | 1.00 | CDK4 (0.34) | CDK4CCND1CCNE1CDK2ALDH1A1 | |
| SCHEMBL213285 | 0.81 | — | — | |
| SCHEMBL213286 | 0.81 | — | — | |
| SCHEMBL251686 | 0.78 | PDPK1 (0.36) | CDK4CCND1CCNE1CDK2ALDH1A1 | |
| SCHEMBL251687 | 0.78 | PDPK1 (0.36) | CDK4CCND1CCNE1CDK2ALDH1A1 | |
| SCHEMBL213938 | 0.76 | CDK4 (0.33) | CDK4CCND1CCNE1CDK2ALDH1A1 | |
| SCHEMBL214346 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL214345 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL29769345 | 0.73 | ALDH1A1 (0.40) | CDK4CCND1CCNE1CDK2ALDH1A1 | |
| SCHEMBL1255596 | 0.73 | ALDH1A1 (0.40) | CDK4CCND1CCNE1CDK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | disclosed |