Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 5/20 | 0.33 |
| ▸ | NOS1 | P29475 | 5/20 | 0.33 |
| ▸ | NOS2 | P35228 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2134321 | 0.94 | — | — | |
| SCHEMBL4572655 | 0.84 | HSD17B3 (0.37) | LMNAMAPTHPGDALDH1A1NOS3 | |
| SCHEMBL4572637 | 0.79 | CYP2D6 (0.39) | LMNAMAPTHPGDALDH1A1MEN1 | |
| SCHEMBL444695 | 0.76 | — | — | |
| SCHEMBL4674692 | 0.73 | — | — | |
| SCHEMBL14398018 | 0.71 | HPGD (0.42) | GAALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL4572636 | 0.71 | CYP2D6 (0.34) | GAALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL329231 | 0.69 | — | — | |
| SCHEMBL6429517 | 0.68 | CYP1A2 (0.43) | CYP1A2GAALMNAMAPTHPGD | |
| SCHEMBL12186371 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117757572-A | Glutinous rice leaf oil, preparation method and application thereof | 广西中烟工业有限责任公司 | 2024-03-26 | — | — | CN | claimed |
| CN-121379730-A | Tobacco spice with glutinous rice flavor and tea flavor and application thereof | 中国烟草总公司郑州烟草研究院 | 2026-01-23 | — | — | CN | disclosed |
| CN-119164745-A | Extraction method and analysis method of volatile aroma components in solid sample | 中国烟草总公司郑州烟草研究院 | 2024-12-20 | — | — | CN | disclosed |
| CN-119144388-A | Green-flavor type rice-flavor essence for cigarettes and application thereof | 广西中烟工业有限责任公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-119081772-A | Tobacco essence with milk-flavored rice flavor and application thereof | 广西中烟工业有限责任公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-117757572-A | Glutinous rice leaf oil, preparation method and application thereof | 广西中烟工业有限责任公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-2445874-B1 | PROCESS OF PREPARATION OF 2-ACETYL-1-PYRROLINE AND A STABLE PRECURSOR THEREOF, ISOTOPICALLY LABELLED OR NOT | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-11-29 | — | — | EP | disclosed |
| EP-2445874-B1 | PROCESS OF PREPARATION OF 2-ACETYL-1-PYRROLINE AND A STABLE PRECURSOR THEREOF, ISOTOPICALLY LABELLED OR NOT | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-11-29 | — | — | EP | disclosed |
| US-20150223501-A1 | NOVEL FLAVOUR COMPOSITIONS WITH IMPROVED FLAVOUR AND/OR FLAVOUR SHELF-LIFE | NESTEC S.A. (CH) | 2015-08-13 | — | — | US | disclosed |
| US-8597706-B2 | Method for synthesizing 2-acetyl-1-pyrroline, stable ketal precursors thereof, and isotopically marked analogs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-12-03 | — | — | US | disclosed |
| US-20130303466-A1 | Chemosensory Receptor Ligand-Based Therapies | ELCELYX THERAPEUTICS, INC. (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130303466-A1 | Chemosensory Receptor Ligand-Based Therapies | ELCELYX THERAPEUTICS, INC. (US) | 2013-11-14 | — | — | US | disclosed |
| EP-2445874-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | Centre National De La Recherche Scientifique CNRS (FR) | 2012-05-02 | — | — | EP | disclosed |
| US-20120100274-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | UNIVERSITE DE MONTPELLIER (FR) | 2012-04-26 | — | — | US | disclosed |
| US-20120100274-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | UNIVERSITE DE MONTPELLIER (FR) | 2012-04-26 | — | — | US | disclosed |
| US-20120100274-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | UNIVERSITE DE MONTPELLIER (FR) | 2012-04-26 | — | — | US | disclosed |
| WO-2012054527-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
| WO-2010149744-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149744-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303466-A1 | Chemosensory Receptor Ligand-Based Therapies | GPR119, TAS1R2, TAS2R1 | CYP1A2 4702/4885GAA 2044/4885LMNA 4196/4885 |
| US-20120100274-A1 | METHOD FOR SYNTHESISING 2-ACETYL-1-PYRROLINE AND THE STABLE PRECURSOR THEREOF, OPTIONALLY ISOTOPICALLY MARKED | SAT1, PDHA1, PTMS | CYP1A2 908/4885GAA 2518/4885LMNA 2869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.