Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249312 | 1.00 | ESR1 (0.48) | ESR1TSHRACHEACP3CYP3A4 | |
| SCHEMBL23249532 | 1.00 | ESR1 (0.48) | ESR1TSHRACHEACP3CYP3A4 | |
| SCHEMBL11401314 | 0.82 | ESR1 (0.45) | ESR1TSHRACHEACP3ALDH1A1 | |
| SCHEMBL10410201 | 0.79 | ESR1 (0.46) | ESR1TSHRACHEACP3ALDH1A1 | |
| SCHEMBL11463024 | 0.79 | ESR1 (0.46) | ESR1TSHRACHEACP3ALDH1A1 | |
| SCHEMBL2550047 | 0.79 | ESR1 (0.46) | ESR1TSHRACHEACP3ALDH1A1 | |
| SCHEMBL9165865 | 0.79 | ESR1 (0.46) | ESR1TSHRACHEACP3ALDH1A1 | |
| SCHEMBL143737 | 0.75 | ESR1 (0.52) | ESR1TSHRACHEACP3CYP3A4 | |
| SCHEMBL3867592 | 0.75 | ESR1 (0.52) | ESR1TSHRACHEACP3CYP3A4 | |
| SCHEMBL2332685 | 0.75 | ESR1 (0.52) | ESR1TSHRACHEACP3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230049481-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2023-02-16 | — | — | US | disclosed |
| US-11155520-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC | 2021-10-26 | — | — | US | disclosed |
| EP-3761790-A1 | PICOLINAMIDES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2021-01-13 | — | — | EP | disclosed |
| US-20200399222-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-12-24 | — | — | US | disclosed |
| WO-2019173665-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2019-09-12 | — | — | WO | disclosed |
| US-20190276404-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2019-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399222-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | ESR1 3596/4885TSHR 2350/4885ACHE 1673/4885 |
| US-20190276404-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | ESR1 3596/4885TSHR 2350/4885ACHE 1673/4885 |
| US-20230049481-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | ESR1 3596/4885TSHR 2350/4885ACHE 1673/4885 |
| US-11155520-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | ESR1 3596/4885TSHR 2350/4885ACHE 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.