Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19640186 | 0.82 | L3MBTL1 (0.44) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21331710 | 0.82 | MAPT (0.43) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19640185 | 0.81 | KDM4E (0.41) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21331704 | 0.81 | MAOA (0.42) | KDM4EMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21331692 | 0.79 | KDM4E (0.40) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19640210 | 0.79 | NPC1 (0.40) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19640196 | 0.77 | LMNA (0.50) | KDM4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL22714672 | 0.77 | HTT (0.50) | KDM4EMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22146466 | 0.77 | KDM4E (0.41) | KDM4EMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17744476 | 0.77 | GAA (0.45) | NPC1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169539-A1 | NOVEL OXA-AND AZA-TRICYCLIC 4-PYRIDONE-3-CARBOXYLIC ACID FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | PHARMARESOURCES (SHANGHAI) CO., LTD. (CN) | 2019-09-12 | — | — | WO | disclosed |