Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21331966 | 1.00 | DDB1 (0.47) | DDB1CRBNMMP1MMP13MAP2K1 | |
| SCHEMBL21332020 | 0.82 | DDB1 (0.51) | DDB1CRBNMMP1MMP13MAP2K1 | |
| SCHEMBL21331977 | 0.79 | FPR1 (0.46) | ALDH1A1FPR1FPR2KMT2A | |
| SCHEMBL21331979 | 0.79 | FPR1 (0.46) | ALDH1A1FPR1FPR2KMT2A | |
| SCHEMBL21332358 | 0.77 | FPR1 (0.41) | FPR1FPR2 | |
| SCHEMBL21332359 | 0.77 | FPR1 (0.41) | FPR1FPR2 | |
| SCHEMBL8530171 | 0.72 | DDB1 (0.44) | DDB1CRBNMMP1MMP13MAP2K1 | |
| SCHEMBL8530170 | 0.72 | DDB1 (0.44) | DDB1CRBNMMP1MMP13MAP2K1 | |
| SCHEMBL1268717 | 0.69 | TSHR (0.69) | MAP2K1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL18117753 | 0.69 | TSHR (0.69) | MAP2K1ALDH1A1ALOX15TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |