Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 13/20 | 0.46 |
| ▸ | FPR2 | P25090 | 10/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | CPS1 | P31327 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21331977 | 1.00 | FPR1 (0.46) | FPR1FPR2MTNR1ACPS1MEN1 | |
| SCHEMBL21332359 | 0.84 | FPR1 (0.41) | FPR1FPR2 | |
| SCHEMBL21332358 | 0.84 | FPR1 (0.41) | FPR1FPR2 | |
| SCHEMBL21331966 | 0.79 | DDB1 (0.47) | FPR1FPR2ALDH1A1KMT2A | |
| SCHEMBL21331968 | 0.79 | DDB1 (0.47) | FPR1FPR2ALDH1A1KMT2A | |
| SCHEMBL18117787 | 0.74 | MTNR1A (0.64) | FPR1FPR2MTNR1AALDH1A1MAPT | |
| SCHEMBL19559399 | 0.74 | MTNR1A (0.64) | FPR1FPR2MTNR1AALDH1A1MAPT | |
| SCHEMBL21342012 | 0.72 | MTNR1A (0.49) | FPR1FPR2MTNR1A | |
| SCHEMBL21342014 | 0.70 | FPR1 (0.53) | FPR1FPR2MTNR1A | |
| SCHEMBL19972418 | 0.70 | FPR1 (0.57) | FPR1FPR2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |