Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 13/20 | 0.38 |
| ▸ | FPR2 | P25090 | 13/20 | 0.38 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21314742 | 1.00 | FPR1 (0.38) | FPR1FPR2DUT | |
| SCHEMBL21341218 | 0.90 | FPR1 (0.37) | FPR1FPR2DUT | |
| SCHEMBL21314762 | 0.82 | DUT (0.32) | DUT | |
| SCHEMBL21314767 | 0.81 | FPR2 (0.59) | FPR1FPR2 | |
| SCHEMBL30832924 | 0.79 | HDAC1 (0.36) | DUT | |
| SCHEMBL21314774 | 0.79 | HDAC1 (0.36) | DUT | |
| SCHEMBL21314771 | 0.79 | HDAC1 (0.36) | DUT | |
| SCHEMBL25868512 | 0.78 | FPR1 (0.37) | FPR1FPR2 | |
| SCHEMBL21340978 | 0.77 | — | — | |
| SCHEMBL21314730 | 0.77 | FPR1 (0.42) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762380-A1 | PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | Bristol-Myers Squibb Company (US) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019173182-A1 | PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-12 | — | — | WO | disclosed |