Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azelaic Acid SCHEMBL28307578 | 0.87 | MAPT (0.67) | LMNAABCC4MAPTFOLH1OR51E2 | |
| Glycolic Acid SCHEMBL11501011 | 0.82 | — | — | |
| Propionic Acid SCHEMBL10898172 | 0.80 | FFAR3 (0.56) | LMNAABCC4MAPTFOLH1TSHR | |
| Glycine SCHEMBL28761665 | 0.80 | — | — | |
| Acetic Acid SCHEMBL27949199 | 0.79 | — | — | |
| SCHEMBL5265719 | 0.79 | — | — | |
| Succinic Acid SCHEMBL15878266 | 0.79 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL28114499 | 0.78 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL4061508 | 0.78 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL15877803 | 0.77 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019172487-A1 | MICROCAPSULES FOR SELF-HEALING CONCRETE USING MICROORGANISMS AND METHOD FOR PRODUCING SAME, AND SELF-HEALING CONCRETE COMPOSITION CONTAINING MICROCAPSULES | 한국과학기술원 | 2019-09-12 | — | — | WO | disclosed |
| CN-100586964-C | Process for the polymerization of olefins in the presence of an anti-fouling agent | TOTAL PETROCHEMICALS RES FELUY | 2010-02-03 | — | — | CN | disclosed |
| CN-1918198-A | Olefin polymerisation process in the presence of an anti-fouling agent | TOTAL PETROCHEMICALS RES FELUY (BE) | 2007-02-21 | — | — | CN | disclosed |
| CN-1072689-A | Reduce the expansile method of latex | ROHM & HAAS (US) | 1993-06-02 | — | — | CN | disclosed |