Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.64 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL4061457 | 0.87 | SLC22A6 (0.69) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Adipic Acid SCHEMBL851390 | 0.87 | LMNA (0.69) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Succinic Acid SCHEMBL28114499 | 0.86 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Sebacic Acid SCHEMBL4053732 | 0.84 | TSHR (0.71) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Azelaic Acid SCHEMBL4051535 | 0.84 | TSHR (0.71) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Butadiene SCHEMBL2257807 | 0.84 | TSHR (0.71) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Octanedioate SCHEMBL4052467 | 0.84 | TSHR (0.71) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Succinic Acid SCHEMBL7194377 | 0.83 | EGLN1 (0.60) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL7095069 | 0.83 | EGLN1 (0.60) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL1200041 | 0.83 | EGLN1 (0.60) | LMNAEGLN1ALKBH5SUCNR1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113675466-A | All-solid-state metal lithium battery and preparation method thereof | 张火锐 | 2021-11-19 | — | — | CN | claimed |
| CN-117720799-A | Degradable high-toughness antibacterial PBAT foaming material | 福州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-113675466-B | All-solid-state metal lithium battery and preparation method thereof | 张火锐 | 2023-02-24 | — | — | CN | disclosed |
| CN-113675466-A | All-solid-state metal lithium battery and preparation method thereof | 张火锐 | 2021-11-19 | — | — | CN | disclosed |
| CN-113675466-A | All-solid-state metal lithium battery and preparation method thereof | 张火锐 | 2021-11-19 | — | — | CN | disclosed |
| CN-110746630-A | Grafted antibacterial degradable preservative film and preparation method and application thereof | 上海海洋大学 | 2020-02-04 | — | — | CN | disclosed |
| EP-3067373-B1 | METHOD FOR PRODUCING VINYLAMINE (CO)POLYMER | MITSUBISHI CHEM CORP (JP) | 2018-06-20 | — | — | EP | disclosed |
| CN-106605038-A | Compound cluster placement in fractures | 施蓝姆伯格技术公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-103608726-B | Photoresist comprising polymer-tethered nanoparticles | 3M创新有限公司 | 2016-11-09 | — | — | CN | disclosed |
| EP-3067373-A1 | METHOD FOR PRODUCING VINYLAMINE (CO)POLYMER | Mitsubishi Rayon Co., Ltd. (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-20160237191-A1 | METHOD FOR PRODUCING VINYLAMINE (CO)POLYMER | MITSUBISHI RAYON CO., LTD. (JP) | 2016-08-18 | — | — | US | disclosed |
| US-7507516-B2 | Toner and method of manufacturing toner | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2009-03-24 | — | — | US | disclosed |
| US-20060292481-A1 | Toner and method of manufacturing toner | KONICA MINOLTA BUSINES TECHNOLOGIES, INC. | 2006-12-28 | — | — | US | disclosed |