Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.64 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27801856 | 0.87 | LMNA (0.69) | LMNAABCC4MAPTOR51E2SLC22A6 | |
| Succinic Acid SCHEMBL4061508 | 0.86 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| SCHEMBL28159191 | 0.84 | — | — | |
| Succinic Acid SCHEMBL29760991 | 0.83 | LMNA (0.67) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL29516623 | 0.83 | LMNA (0.67) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL5221290 | 0.83 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL1200041 | 0.83 | EGLN1 (0.60) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL7752291 | 0.83 | EGLN1 (0.60) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL7095069 | 0.83 | EGLN1 (0.60) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Succinic Acid SCHEMBL181452 | 0.83 | LMNA (0.67) | LMNAEGLN1ALKBH5SUCNR1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104644566-B | Slow-release azithromycin lactobionate injection and preparation method thereof | 北京红太阳药业有限公司 | 2017-01-11 | — | — | CN | claimed |
| US-11820939-B2 | Nanogels for delayed gelation | CONOCOPHILLIPS COMPANY (US) | 2023-11-21 | — | — | US | disclosed |
| CN-110872506-B | Nanogel for delayed gelation | 科诺科菲利浦公司 | 2023-03-28 | — | — | CN | disclosed |
| US-20220325170-A1 | NANOGELS FOR DELAYED GELATION | CONOCOPHILLIPS COMPANY (US) | 2022-10-13 | — | — | US | disclosed |
| US-11396624-B2 | Nanogels for delayed gelation | CONOCOPHILIPS COMPANY (US) | 2022-07-26 | — | — | US | disclosed |
| CN-110872506-A | Nanogel for delayed gelation | 科诺科菲利浦公司 | 2020-03-10 | — | — | CN | disclosed |
| CN-109411237-A | A kind of electrolyte for electrolytic capacitor and preparation method thereof | 南通瑞达电子材料有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-104644566-B | Slow-release azithromycin lactobionate injection and preparation method thereof | 北京红太阳药业有限公司 | 2017-01-11 | — | — | CN | disclosed |