Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21023522 | 0.78 | OPRM1 (0.46) | OPRD1OPRM1OPRK1NR1I2KCNH2 | |
| SCHEMBL21338058 | 0.78 | OPRM1 (0.46) | OPRD1OPRM1OPRK1NR1I2KCNH2 | |
| SCHEMBL17696682 | 0.69 | OPRD1 (0.42) | OPRD1OPRM1OPRK1CYP2D6CHRNA7 | |
| SCHEMBL20170829 | 0.68 | OPRD1 (0.46) | OPRD1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL20170682 | 0.66 | OPRM1 (0.39) | OPRD1OPRM1OPRK1CYP2D6SIGMAR1 | |
| SCHEMBL21023520 | 0.65 | OPRM1 (0.35) | OPRD1OPRM1OPRK1 | |
| SCHEMBL18056759 | 0.65 | OPRM1 (0.54) | OPRD1OPRM1OPRK1CYP2D6CHRNA7 | |
| SCHEMBL13707246 | 0.64 | OPRM1 (0.49) | OPRD1OPRM1OPRK1 | |
| SCHEMBL15250867 | 0.64 | OPRM1 (0.41) | OPRD1OPRM1OPRK1CYP2D6CTDSP1 | |
| SCHEMBL18104558 | 0.64 | OPRM1 (0.44) | OPRD1OPRM1OPRK1NR1I2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019500-B1 | NALMEFENE SALTS AS MEDICAMENTS FOR REDUCING ALCOHOL CONSUMPTION OR FOR PREVENTING EXCESSIVE ALCOHOL CONSUMPTION | H LUNDBECK AS (DK) | 2019-09-11 | — | — | EP | disclosed |