Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170860 | 0.83 | OPRM1 (0.50) | OPRD1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL14679553 | 0.83 | OPRM1 (0.50) | OPRD1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL14679550 | 0.83 | OPRM1 (0.50) | OPRD1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL14679543 | 0.83 | OPRM1 (0.50) | OPRD1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL17696682 | 0.82 | OPRD1 (0.42) | OPRD1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL20170754 | 0.79 | OPRM1 (0.41) | OPRD1OPRM1OPRK1SIGMAR1 | |
| SCHEMBL13049580 | 0.76 | OPRM1 (0.49) | OPRD1OPRM1OPRK1 | |
| SCHEMBL21859469 | 0.75 | OPRM1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL20631279 | 0.73 | OPRM1 (0.48) | OPRD1OPRM1OPRK1 | |
| SCHEMBL16509913 | 0.73 | OPRM1 (0.48) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |