Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21338898 | 1.00 | DPP4 (0.40) | DPP4DPP9DPP7DPP8KCNH2 | |
| SCHEMBL17902422 | 0.88 | AOC3 (0.38) | DPP4DPP9DPP7DPP8KCNH2 | |
| SCHEMBL21338900 | 0.87 | DPP4 (0.39) | DPP4DPP9DPP7DPP8KCNH2 | |
| SCHEMBL21339027 | 0.87 | DPP4 (0.39) | DPP4DPP9DPP7DPP8KCNH2 | |
| SCHEMBL22041429 | 0.87 | DPP4 (0.39) | DPP4DPP9DPP7DPP8KCNH2 | |
| SCHEMBL21339034 | 0.87 | DPP4 (0.39) | DPP4DPP9DPP7DPP8KCNH2 | |
| SCHEMBL21338895 | 0.87 | DPP4 (0.39) | DPP4DPP9DPP7DPP8KCNH2 | |
| SCHEMBL28265840 | 0.84 | AOC3 (0.40) | DPP4DPP9DPP7DPP8KCNH2 | |
| SCHEMBL15087385 | 0.80 | MME (0.39) | DPP4DPP9DPP7DPP8KCNH2 | |
| SCHEMBL21339246 | 0.79 | DPP8 (0.39) | DPP4DPP9DPP7DPP8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230049481-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2023-02-16 | — | — | US | disclosed |
| US-11155520-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC | 2021-10-26 | — | — | US | disclosed |
| US-20200399222-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-12-24 | — | — | US | disclosed |
| US-20190276404-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2019-09-12 | — | — | US | disclosed |
| WO-2019173665-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399222-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | DPP4 557/4885DPP9 322/4885DPP7 146/4885 |
| US-20190276404-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | DPP4 557/4885DPP9 322/4885DPP7 146/4885 |
| US-20230049481-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | DPP4 557/4885DPP9 322/4885DPP7 146/4885 |
| US-11155520-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | DPP4 557/4885DPP9 322/4885DPP7 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.