Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21339230 | 0.88 | DPP4 (0.40) | AOC3HTTDPP4DPP8DPP9 | |
| SCHEMBL21338898 | 0.88 | DPP4 (0.40) | AOC3HTTDPP4DPP8DPP9 | |
| SCHEMBL17902572 | 0.87 | HTT (0.40) | HTTALDH1A1KDM4EKLK7NPC1 | |
| SCHEMBL17902583 | 0.87 | HTT (0.40) | HTTALDH1A1KDM4EKLK7NPC1 | |
| SCHEMBL28718206 | 0.87 | HTT (0.40) | HTTALDH1A1KDM4EKLK7NPC1 | |
| SCHEMBL17902586 | 0.87 | HTT (0.40) | HTTALDH1A1KDM4EKLK7NPC1 | |
| SCHEMBL22400672 | 0.87 | HTT (0.40) | HTTALDH1A1KDM4EKLK7NPC1 | |
| SCHEMBL17902261 | 0.87 | HTT (0.40) | HTTALDH1A1KDM4EKLK7NPC1 | |
| SCHEMBL22400670 | 0.87 | HTT (0.40) | HTTALDH1A1KDM4EKLK7NPC1 | |
| Hydrochloric Acid SCHEMBL20549211 | 0.86 | HTT (0.39) | HTTALDH1A1KDM4EKLK7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| EP-3808181-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-3240773-B9 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-3240424-B1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-16 | — | — | EP | disclosed |
| EP-3240773-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-06-03 | — | — | EP | disclosed |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2020-03-17 | — | — | US | disclosed |
| US-10182568-B2 | Use of picolinamide compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-22 | — | — | US | disclosed |
| WO-2016122802-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016109257-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10182568-B2 | Use of picolinamide compounds as fungicides | PFAS, FKBP2, FKBP14 | AOC3 1542/4885HTT 3837/4885DPP4 1068/4885 |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | AOC3 1594/4885HTT 3579/4885DPP4 477/4885 |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | AOC3 1594/4885HTT 3579/4885DPP4 477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.