SCHEMBL21339902

SCHEMBL21339902

N/N=C(\NN)c1ccc(Br)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGG1 O15527 1/20 0.52
IDO1 P14902 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
GSK3B P49841 2/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
MAPT P10636 1/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC22A2 O15244 1/20 0.35
SLC22A1 O15245 1/20 0.35
SLC22A3 O75751 1/20 0.35
PLAU P00749 1/20 0.35
F2 P00734 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24100590 0.81 OGG1 (0.41) OGG1CES2CES1GSK3BCA1
SCHEMBL24484070 0.81 OGG1 (0.41) OGG1CES2CES1GSK3BCA1
SCHEMBL20777964 0.80 MASP2 (0.39) CA1CA2MAPTKDM4ENPC1
SCHEMBL23118889 0.77 TSHR (0.50) CES2CES1CA1CA2ALDH1A1
SCHEMBL22587125 0.75 HDAC3 (0.46) CA1CA2MAPTNOS1
Hydrochloric Acid SCHEMBL28483887 0.75 OGG1 (0.48) OGG1IDO1GSK3BMAPTKDM4E
SCHEMBL28489929 0.75 OGG1 (0.44) OGG1IDO1CES2CES1GSK3B
SCHEMBL20285854 0.74 SMN1; SMN2 (0.47) IDO1CA2MAPTALDH1A1GAA
SCHEMBL21339965 0.72 MAPT (0.61) CA1CA2MAPTNPC1ALDH1A1
SCHEMBL22643986 0.71 TSHR (0.52) CES2CES1CA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019171234-A9 HETEROCYCLIC COMPOUNDS AS FUNGICIDES PI INDUSTRIES LTD. (IN) 2020-01-09 WO disclosed
WO-2019171234-A1 HETEROCYCLIC COMPOUNDS AS FUNGICIDES PI INDUSTRIES LTD. (IN) 2019-09-12 WO disclosed