SCHEMBL21339906

SCHEMBL21339906

Nc1ccc(-c2n[nH]c(C(F)(F)F)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 5/20 0.52
RAB9A P51151 3/20 0.51
NPC1 O15118 2/20 0.51
LMNA P02545 1/20 0.51
XDH P47989 1/20 0.45
KIF11 P52732 2/20 0.42
MAPT P10636 3/20 0.39
KDM4E B2RXH2 2/20 0.39
METAP2 P50579 1/20 0.38
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
KMT2A Q03164 2/20 0.37
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP19A1 P11511 1/20 0.37
DGAT1 O75907 1/20 0.36
PTGS2 P35354 1/20 0.35
NR1H2 P55055 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17207531 0.84 AOC3 (0.50) AOC3RAB9ANPC1LMNAXDH
SCHEMBL31327475 0.82 AOC3 (0.52) AOC3RAB9ANPC1XDHKIF11
SCHEMBL15299217 0.82 AOC3 (0.52) AOC3RAB9ANPC1XDHKDM4E
SCHEMBL11642290 0.81 NR1H2 (0.55) AOC3RAB9ANPC1LMNAXDH
SCHEMBL16599546 0.80 NPC1 (0.47) AOC3RAB9ANPC1LMNAXDH
SCHEMBL16328874 0.79 AOC3 (0.50) AOC3RAB9ANPC1XDHDGAT1
Hydrochloric Acid SCHEMBL9573625 0.79 ATAD2 (0.57) AOC3RAB9ANPC1LMNAMAPT
SCHEMBL26464405 0.77 NPC1 (0.67) RAB9ANPC1LMNAKIF11MAPT
SCHEMBL1832874 0.76 ABCC8 (0.52) AOC3RAB9ANPC1LMNAXDH
SCHEMBL7512048 0.75 AOC3 (0.40) AOC3RAB9AXDHMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019171234-A1 HETEROCYCLIC COMPOUNDS AS FUNGICIDES PI INDUSTRIES LTD. (IN) 2019-09-12 WO disclosed