Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22815107 | 0.84 | LRRK2 (0.50) | ACVR1LRRK2PDGFRAFERLTK | |
| SCHEMBL24822055 | 0.84 | LRRK2 (0.50) | ACVR1LRRK2PDGFRAFERLTK | |
| SCHEMBL727511 | 0.81 | ALDH1A1 (0.37) | LRRK2PDGFRAFERLTKCDK8 | |
| SCHEMBL24976109 | 0.81 | ALDH1A1 (0.37) | LRRK2PDGFRAFERLTKCDK8 | |
| SCHEMBL17949690 | 0.76 | CA12 (0.40) | LRRK2PDGFRALTKCDK8DYRK1B | |
| SCHEMBL30340726 | 0.76 | CA12 (0.40) | LRRK2PDGFRALTKCDK8DYRK1B | |
| SCHEMBL20503690 | 0.76 | CA12 (0.40) | LRRK2PDGFRALTKCDK8DYRK1B | |
| SCHEMBL30096606 | 0.76 | CA12 (0.40) | LRRK2PDGFRALTKCDK8DYRK1B | |
| SCHEMBL23044043 | 0.72 | KDM4E (0.41) | LRRK2PDGFRALTKCDK8DYRK1B | |
| SCHEMBL26691333 | 0.72 | MEN1 (0.31) | MEN1ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11007520-B2 | Covalently modified surfaces, kits, and methods of preparation and use | Berkeley Lights, Inc. (US) | 2021-05-18 | — | — | US | disclosed |
| US-20190275516-A1 | Covalently Modified Surfaces, Kits, and Methods of Preparation and Use | Berkeley Lights, Inc. (US) | 2019-09-12 | — | — | US | disclosed |